Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester, (S)- - Names and Identifiers
Name | Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester
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Synonyms | Z-VAL-OL Z-Valinol CBZ-L-VALINOL Cbz-L-Valinol N-CARBOBENZOXY-L-VALINOL N-Benzyloxycarbonyl-L-valinol (S)-benzyl (1-hydroxy-3-methylbutan-2-yl)carbamate Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, benzyl ester, L- Carbamicacid, [(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester, (S)- Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester Carbamic acid, N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester
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CAS | 6216-65-5
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Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester, (S)- - Physico-chemical Properties
Molecular Formula | C13H19NO3
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Molar Mass | 237.29 |
Storage Condition | Sealed in dry,Room Temperature |
Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester, (S)- - Introduction
Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester is an organic compound whose chemical name is Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester. Its properties are as follows:
Appearance: White crystalline powder
Molecular formula: C19H23NO3
Molecular weight: 317.4g/mol
Melting point: 72-74 degrees Celsius
Solubility: Slightly soluble in water, soluble in ethanol, methanol and dichloromethane and other organic solvents
Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester is mainly used for protecting group reactions in organic synthesis. It can be used in the reaction of protecting the amino group and the hydroxyl group, and the protecting group can be easily removed when necessary. By protecting group reactions, certain functional groups in the molecule can be selectively protected so that other functional groups are not disturbed during the synthesis.
Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester is usually prepared by reacting L-valinol with benzachloroformic acid (Cbz-Cl) under alkaline conditions. The target compound can be obtained by purifying the reaction product.
Regarding safety information, Carbamic acid,N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-, phenylmethyl ester has low toxicity under normal operating conditions. However, as a chemical substance, it should be used in accordance with the safe practice of the laboratory, including wearing appropriate protective equipment and avoiding contact with sensitive parts such as eyes, skin and mouth. During storage and handling, care should be taken to avoid contact with strong oxidants and strong acids to avoid harmful gases. If skin contact or inhalation occurs, wash the affected area immediately and seek medical help.
Last Update:2024-04-10 22:29:15